NEW hardcover

Sample Size Calculations in Clinical Research, Second Edition Chapman HallCRC Biostatistics Series Chow, SheinChung; Wang, Hansheng and Shao, Jun

Focusing on an integral part of pharmaceutical development, Sample Size Calculations in Clinical Research, Second Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development It provides sample size formulas and procedures for testing equality, noninferioritysuperiority, and equivalenceA comprehensive and unified presentation of statistical concepts and practical applications, this book highlights the interactions between clinicians and biostatisticians, includes a wellbalanced summary of current and emerging clinical issues, and explores recently developed statistical methodologies for sample size calculation Whenever possible, each chapter provides a brief history or background, regulatory requirements, statistical designs and methods for data analysis, realworld examples, future research developments, and related referencesOne of the few books to systematically summarize clinical research procedures, this edition contains new chapters that focus on three key areas of this field Incorporating the material of this book in your work will help ensure the validity and, ultimately, the success of your clinical studies